American Academy of Orthopaedic Surgeons and the International Cellular Medicine Society have suggested guidelines, many of which are included below:
Platelet-rich plasma injections are not typically recommended for the most severe cases of osteoarthritis.
Platelet-rich plasma injections helped the joint if the arthritis is less than 75% damage on the x-rays. Platelet-rich plasma itself is not the cure, a patient needs to do exercise, weight loss.
Blood is drawn from the vein and centrifuge by using advanced efficient Emcyte centrifuge with greater G force which provides 7-9 times concentration of platelets, degranulated and combined with little red blood cells and injected into the joint. May repeat every 4 weeks. Patient may experience little pain after injecting PRP that can be controlled by applying cold compresses and patient can take Tylenol as needed. We recommend patient not to take NSAIDs after PRP injection. The improvement in the joint can take 12 weeks. If needed patient may need treatment once a year to maintain the joint and to prevent it from degeneration.